Third seed Anabel Medina Garrigues was a shock casualty at the BGL Luxembourg Open.
She was sent crashing out by qualifier Kirsten Flipkens.
Medina Garrigues, of Spain, is ranked almost 60 places above her opponent but that mattered little as the Belgian ran out a 7-5 6-3 winner to move into the third round.
Sixth seed Sabine Lisicki also safely progressed with a 7-6 (7/1) 6-4 win over wild card Polona Hercog of Slovenia while Timea Bacsinszky defeated Roberta Vinci 6-2 6-2.
In the first round, fourth seed Daniela Hantuchova thrashed German Tatjane Malek 6-1 6-0 in 52 minutes.
It was by no means a perfect performance by the Slovakian who served four double faults but she had great success on her first serve.
Fifth seed Yanina Wickmayer also made it through but was pushed harder by Alexandra Dulgheru with the Belgian winning 6-3 7-6 (7/4).
Also through was Lucie Hradecka who beat qualifier Catalina Castano 7-6 (7/4) 6-2.(source)
Russian Nadia Petrova, stung by US teenager Melanie Oudin in the fourth round of the US Open, continued her rebound Wednesday by reaching the quarter-finals of the WTA Bell Challenge.
Nadia Petrova, who was coming off a shocking fourth-round loss to Melanie Oudin at the US Open, cruised to a 6-2, 6-0 win over Carly Gullickson in the first round of the WTA Bell Challenge.